Angeliki Chroni Selected Research

Apolipoprotein E3

1/2022	Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK.
12/2018	Thermodynamic destabilization and aggregation propensity as the mechanism behind the association of apoE3 mutants and lipoprotein glomerulopathy.
10/2017	Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells.
1/2014	apoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL.
1/2013	Thermodynamic and structural destabilization of apoE3 by hereditary mutations associated with the development of lipoprotein glomerulopathy.
1/2011	Biophysical analysis of apolipoprotein E3 variants linked with development of type III hyperlipoproteinemia.

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Angeliki Chroni Research Topics

Disease

10	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2008
8	Neuroblastoma 01/2021 - 11/2010
8	Atherosclerosis 12/2020 - 04/2004
8	Dyslipidemias (Dyslipidemia) 01/2015 - 08/2004
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 10/2011
5	Hypertriglyceridemia 01/2014 - 04/2004
3	Hypercholesterolemia 01/2022 - 03/2005
3	Coronary Artery Disease (Coronary Atherosclerosis) 12/2020 - 07/2011
3	Lipoprotein Glomerulopathy 12/2018 - 01/2013
2	Wounds and Injuries (Trauma) 01/2019 - 01/2018
2	Hyperlipoproteinemia Type III (Broad Beta Disease) 01/2014 - 01/2011
2	Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency) 06/2011 - 11/2005
2	Tangier Disease 08/2006 - 04/2004
2	Coinfection 11/2005 - 08/2004
1	Adenocarcinoma 01/2020
1	Stab Wounds (Stab Wound) 01/2019
1	Brain Injuries (Brain Injury) 01/2019
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2019
1	Ischemic Stroke 01/2019
1	Stroke (Strokes) 01/2019
1	Inflammation (Inflammations) 01/2018
1	Amyloidosis 11/2015
1	Ankylosing Spondylitis 09/2015
1	Kidney Diseases (Kidney Disease) 04/2014
1	Rare Diseases (Rare Disease) 04/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2011
1	Hypoalphalipoproteinemias (Hypoalphalipoproteinemia) 08/2006
1	Hyperlipidemias (Hyperlipidemia) 03/2005

Drug/Important Bio-Agent (IBA)

12	Apolipoproteins E (ApoE)IBA 01/2022 - 04/2004
12	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2020 - 04/2004
9	Lipoproteins (Lipoprotein)IBA 01/2022 - 01/2011
9	Apolipoprotein E4IBA 01/2021 - 09/2008
8	ApolipoproteinsIBA 01/2019 - 04/2006
7	LipidsIBA 01/2022 - 04/2006
6	HDL CholesterolIBA 01/2022 - 08/2006
6	Apolipoprotein E3IBA 01/2022 - 01/2011
6	CholesterolIBA 01/2019 - 04/2004
6	Protein Isoforms (Isoforms)IBA 12/2018 - 11/2010
4	HDL LipoproteinsIBA 01/2019 - 08/2004
4	Peptides (Polypeptides)IBA 01/2019 - 05/2014
4	Amyloid (Amyloid Fibrils)IBA 01/2018 - 11/2010
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2010
3	AntioxidantsIBA 01/2020 - 06/2011
2	LigandsIBA 01/2019 - 01/2014
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 05/2014
2	Triglycerides (Triacylglycerol)IBA 01/2014 - 03/2005
2	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 07/2011 - 08/2004
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2011 - 03/2005
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 08/2006 - 04/2004
1	Coloring Agents (Dyes)IBA 01/2022
1	Evans Blue (Blue, Evans)FDA Link 01/2022
1	PhenolsIBA 01/2021
1	Lipoxygenase (Lipoxygenase-1)IBA 01/2020
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 01/2019
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2018
1	cellulose synthaseIBA 01/2018
1	Phosphatidic Acids (Phosphatidic Acid)IBA 01/2018
1	EnzymesIBA 01/2018
1	Complement System Proteins (Complement)IBA 01/2018
1	Complement Factor H (Factor H)IBA 01/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2017
1	Monoclonal AntibodiesIBA 01/2015
1	Amino Acids FDA Link 04/2014
1	LDL Receptors (LDL Receptor)IBA 01/2011
1	Biological ProductsIBA 01/2008
1	Phospholipid Transfer ProteinsIBA 01/2008
1	TransferasesIBA 01/2008
1	LecithinsIBA 01/2008
1	Adenosine Triphosphate (ATP)IBA 01/2008
1	oxidized low density lipoproteinIBA 03/2005
1	Phospholipids (Phosphatides)FDA LinkGeneric 03/2005
1	Glutamic Acid (Glutamate)FDA Link 08/2004
1	Alanine (L-Alanine)FDA Link 08/2004

Therapy/Procedure

2	Therapeutics 01/2015 - 07/2011